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Bladder cancer

Bladder cancer starts in the cells of the bladder. Blood in the urine is the most common sign and may come and go without pain; always have blood in the urine investigated, even the first time or if there is only a small amount.

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  • Bladder cancer develops when cells in the bladder lining grow out of control. Most tumours start in urothelial cells.
  • Visible blood in the urine is the main warning sign. It may be painless, happen only once and then temporarily disappear.
  • Blood in the urine does not automatically mean cancer; an infection, stone, prostate problem or another condition may also cause it. Investigation is still needed.
  • A single urine test does not establish the diagnosis. Imaging, an examination inside the bladder and tissue testing are usually needed.
  • Treatment and outlook depend on the type, grade and stage, particularly whether the tumour has grown into the bladder muscle and whether it has spread.
  • Non-muscle-invasive bladder cancer is often removed through the urethra and sometimes treated with medicines put into the bladder. Regular examinations inside the bladder remain important because the disease may return.
  • Muscle-invasive disease may require a combination of chemotherapy, surgery or radiotherapy. The treatment team discusses what is most suitable medically and personally.
  • Smoking is the main avoidable risk factor. Stopping also helps after diagnosis and improves overall fitness for treatment.

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